Viagra dilates epicardial coronary arteries.

It has an intermediate opinion on myocardial ischemia compared with isosorbide dinitrate and medicine.
Do PDE5 Inhibitors Precipitate Acute Cardiac Events?
Shortly after loss of the rank PDE5 inhibitor, sildenafil , there were anecdotal reports of acute cardiac events (including cardiac kill and MI) in men who were receiving this functionary.
The questions that arose included: (1) was the PDE5 inhibitor triggering these events, or (2) were these events due to the increased oxygen postulation of sexual trait, or (3) would these events have occurred unrelated to the learned profession, given the ages of the patients and their underlying risk factors?
In magnitude to response these questions several analyses have been performed.
Mittleman et al pooled data from 120 clinical trials of viagra conducted from 1993 to 2001, involving over 7400 viagra and 5700 medicament patients who received double-blind therapy, and over 11 500 patients who received open-label sildenafil .
The rate of MI or cardiovascular demise was 0.91 (95% CI=0.52-1.48) per 100 person-years in the sildenafil-treated patients vs 0.84 (95% CI=0.39-1.60) per 100 patient-years in the medicinal drug patients.
In open radioisotope studies, the rate of MI or change in patients on viagra was even lower at 0.56 (95% CI=0.44-0.72) per 100 patient-years activity.
The authors concluded that rates of MI and cardiovascular state were low and comparable between sildenafil and medicament treatments.
These results confirmed earlier reports by Morales et al , Padma-Nathan et al , Steers et al , Christiansen et al , as well as a drawing by Olsson, which was specifically conducted in patients with known cardiovascular disease.
Several similar analyses have recently been reported for cialis.
In the ordinal info by Emmick et al , the frequency of MI across cialis double-blind studies in >2500 patients receiving cialis was 0.28 per 100 patient-years vs in >1200 medicament patients in whom the relative incidence was 1.1 per 100 patient-years.
This is a part of article Viagra dilates epicardial coronary arteries. Taken from "Cialis Viagra Levitra Effects" Information Blog